The biological role for copper commenced with the appearance of oxygen in earth's atmosphere. Copper proteins have diverse roles in biological electron transport and oxygen transportation, processes that exploit the easy interconversion of Cu(I) and Cu(II). 

Copper compounds in liquid form are used as a wood preservative, particularly in treating original portion of structures during restoration of damage due to dry rot.

Together with zinc, copper wires may be placed over non-conductive roofing materials to discourage the growth of moss.

Textile fibers use copper to create antimicrobial protective fabrics, as do ceramic glazes, stained glass and musical instruments.

Electroplating commonly uses copper as a base for other metals such as nickel.

A small part of copper supply is used in production of compounds for nutritional supplements and fungicides in agriculture.